For just as the soul separated from the body is death of the body, so too the separation of God from the soul is the death of the soul. And this is real death - the death of the soul.

… This is real death, the soul’s withdrawal from divine grace and its attachment to sin. To those who have intellection this is the death from which to flee and of which to dread. To those who have good understanding it is more dreadful than torment in Gehenna. That is why we flee it with our every power. We have cast out everything, left everything, renounced everyone, both relationships and business, and desires, that is, everything that destroys us and separates us from God and from everything out of which such a death exists. For one who fears and guards against this [the death of the soul], the coming death of the flesh is not so terrible, for having real life in oneself, it moreover at death [the death of the body] becomes unalterable from the person. For just as the death of the soul is real death, so too the life of the soul is real life. The life of the soul is its union with God, just as the life of the body is its union with the soul.

~St. Gregory Palamas, A Treatise on the Spiritual Life

It’s pretty simple, really. The more we truly care about our bodies, the more we must care about our souls, and the more we truly care about our souls, the more we must never become separated from God. Priorities become crystal clear.